It　is　difficult　but　significant　to　describe　the　flux　variation　for　the　membrane　filtration　process　with　complex　combined　filtration　mechanisms.　In　this　paper,　the　steady　membrane　frontal　area　(K)　was　proposed　to　improve　the　predictive　accuracy　of　cake-complete　model　for　combined　fouling　mechanisms　of　complete　blocking　and　cake　filtration.　Meanwhile,　the　transition　point　when　the　fouling　mechanisms　changed　from　combined　complete　blocking　and　cake　filtration　into　individual　cake　filtration　could　also　be　analyzed　under　different　conditions.　The　results　showed　that　the　predictions　of　the　proposed　model　had　good　agreements　with　experimental　data　under　different　conditions　for　bovine　serum　albumin　(BSA)　solution.　Meanwhile,　the　proposed　combined　model　possess　higher　accuracy　(relative　error　(sigma)　over　bar　=1.83%)　than　cake　filtration　((sigma)　over　bar　=7.36%),　complete　blocking　((sigma)　over　bar　=15.90%)　and　pore　blockage-cake　((sigma)　over　bar　=5.54%)　model.　Moreover,　the　transition　point　appeared　earlier　at　higher　pressure　and　concentration.　And　larger　K　was　obtained　at　higher　concentration　and　lower　pressure　which　represented　less　fouling　caused　by　complete　blocking.　In　addition,　the　application　of　the　proposed　model　was　validated　not　only　by　different　suspensions　but　also　by　different　membranes.