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学者姓名:王群
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Abstract :
磁分离是从生物样本中富集特定目标物的常用方法。传统特异性磁分离方法一般通过将抗体与磁珠偶联获得免疫磁珠的方式用于特定目标物的捕获,但由于抗体有成本高、捕获目标物后不易释放等缺点,免疫磁珠难以满足众多研究领域对同时满足目标物大批量、高特异性富集的需求。核酸适配体同抗体一样具备目标物高特异性捕获的能力,相较抗体具有制备成本低、结构简单和化学稳定性高等优点,更适合用来大批量、高特异性富集特定目标物,因此在本研究中,本文利用石墨烯对单链和双链核酸的吸附能力不同的特性,以CD63适配体为例设计了一套可以将适配体展示于石墨烯表面并用于捕获、富集和释放目标物的方法。该设计主要包括2个单元,一是可以贴附于石墨烯表面并将CD63适配体展示于石墨烯外的双链寡核苷酸支架,二是采用与支架足部序列互补的单链寡核苷酸,将所捕获的目标物从石墨烯表面解吸附。本研究首先以氧化石墨烯(GO)纸为石墨烯界面,通过对支架或CD63蛋白等进行荧光标记,并对比支架释放前后及CD63蛋白捕获前后GO纸表面荧光强度变化表示其支架释放效果与CD63蛋白捕释情况,随后应用氨基修饰的石墨烯壳铁氮磁珠搭载CD63适配体双链支架,用于捕获细胞裂解液中CD63蛋白。结果表明,该支架可以将适配体展示于石墨烯表面捕获CD63蛋白并可以可控释放,使用挑选的改性石墨烯磁珠搭载该适配体双链支架,可以用于细胞裂解液中CD63蛋白的捕获。该方法有望实现多种蛋白质的特异性富集或通过捕获外泌体膜蛋白而富集外泌体等多种用途。
Keyword :
磁分离 磁分离 石墨烯 石墨烯 适配体 适配体 生物分离 生物分离
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GB/T 7714 | 潘逸群 , 徐瑗聪 , 王群 et al. 用于生物分离的石墨烯表面可控释适配体支架的设计及实验验证 [J]. | 中国生物化学与分子生物学报 , 2024 , 40 (08) : 1132-1143 . |
MLA | 潘逸群 et al. "用于生物分离的石墨烯表面可控释适配体支架的设计及实验验证" . | 中国生物化学与分子生物学报 40 . 08 (2024) : 1132-1143 . |
APA | 潘逸群 , 徐瑗聪 , 王群 , 王明连 . 用于生物分离的石墨烯表面可控释适配体支架的设计及实验验证 . | 中国生物化学与分子生物学报 , 2024 , 40 (08) , 1132-1143 . |
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Abstract :
磁流变阻尼器不仅具有阻尼快速响应、良好的温度稳定性、内部结构简单等优势,而且可以通过调节控制电流使阻尼器的出力值连续变化,实现阻尼力可控.由于磁流变阻尼器阻尼特性与内部磁流变液的磁流变效应有关,具体表现非常复杂,现有力学模型目精度不足,无法精确描述磁流变阻尼器的阻尼特性.在磁流变阻尼器力学性能测试基础上,应用分段拟合函数方法同时结合反正切函数模型改进模型,并辨识改进后力学模型中各参数.将改进后的Bingham模型与实际测试出力值进行对比,结果表明改进后的Bingham模型能够很好地解决Bingham力学模型在非线性滞回阶段出力值曲线与实际测试数据不符的问题,改进后模型总体出力值曲线与阻尼器实际出力值基本相同,模型精度大幅提升.此种改进方法为磁流变阻尼器建立高精度力学模型提供参考.
Keyword :
Bingham模型 Bingham模型 参数辨识 参数辨识 磁流变阻尼器 磁流变阻尼器 非线性滞回 非线性滞回
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GB/T 7714 | 王群 , 马继超 , 朱雨睿 et al. 磁流变阻尼器Bingham力学模型改进及参数辨识 [J]. | 机械设计与制造 , 2024 , 395 (1) : 10-13,19 . |
MLA | 王群 et al. "磁流变阻尼器Bingham力学模型改进及参数辨识" . | 机械设计与制造 395 . 1 (2024) : 10-13,19 . |
APA | 王群 , 马继超 , 朱雨睿 , 郭海霞 . 磁流变阻尼器Bingham力学模型改进及参数辨识 . | 机械设计与制造 , 2024 , 395 (1) , 10-13,19 . |
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Abstract :
Homogeneously dispersed ultrafine CoFe2O4 nanoparticles embedded within N-doped carbon nanofibers (named as CFO@NCNFs) have been fabricated via electrospinning and following heat treatment procedures. The dielectric and magnetic parameters of CFO@NCNFs/paraffin wax composites are regulated through adjusting the concentration of CoFe2O4 to obtain good impedance matching and excellent microwave absorption (MA) properties. Benefiting from the unique structure involving CoFe2O4 @onion-like carbon nanospheres and 3D conductive NCNFs network, as well as the synergistic mechanism between ultrasmall magnetic CoFe2O4 nano-particles and light mass dielectric NCNFs. The CFO@NCNFs-5 exhibit outstanding MA properties at only 20 wt% filler loading and minimum reflection loss (RL) achieves-47.9 dB (surpass 99.9% MA) at 9.2 GHz with a thin thickness of merely 1.7 mm, and the corresponding effective absorption bandwidth (RL <-10 dB) achieves 5.4 GHz (6.5-11.9 GHz). Moreover, the effective absorption bandwidth (EAB) can be obtained in multiband (3.9-18.0 GHz) by adjusting the thickness of sample layer. Our work indicates that the appropriate incorporation of ultrafine CoFe2O4 nanoparticles encapsulated in NCNFs is a versatile and high-efficiency strategy to integrate lightweight and excellent properties of magnetic carbon-based absorbers.
Keyword :
CoFe 2 O 4 nanoparticles CoFe 2 O 4 nanoparticles N-doped N-doped Carbon nanofibers Carbon nanofibers Electromagnetic Electromagnetic Microwave absorption Microwave absorption
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GB/T 7714 | Li, Xiaoqiang , Yu, Chuanjin , Guan, Guangguang et al. Magnetic nitrogen-doped carbon nanofibers containing homogeneously dispersed CoFe2O4 nanoparticles with lightweight and efficient microwave absorption performance [J]. | JOURNAL OF ALLOYS AND COMPOUNDS , 2023 , 965 . |
MLA | Li, Xiaoqiang et al. "Magnetic nitrogen-doped carbon nanofibers containing homogeneously dispersed CoFe2O4 nanoparticles with lightweight and efficient microwave absorption performance" . | JOURNAL OF ALLOYS AND COMPOUNDS 965 (2023) . |
APA | Li, Xiaoqiang , Yu, Chuanjin , Guan, Guangguang , Wang, Ping , Zheng, Xiaolei , Shen, Chenjie et al. Magnetic nitrogen-doped carbon nanofibers containing homogeneously dispersed CoFe2O4 nanoparticles with lightweight and efficient microwave absorption performance . | JOURNAL OF ALLOYS AND COMPOUNDS , 2023 , 965 . |
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Abstract :
To develop a new material with low emissivity in the range of the 3???5 ??m band, the present work reports a CuNiAg alloy/Ni???Ag-doped Cu4O3 one-dimensional photonic crystal prepared by reactive sputtering and correlates the effect of nickel and silver on the structural and infrared spectral properties. The morphology, structure and infrared spectral properties of the CuNiAg alloy/Ni???Ag-doped Cu4O3 1DPC were studied by FESEM, XRD, and an IR-2 dual-wavelength emissivity instrument. The doping of Ni and Ag impeded phase formation, and the Cu2O and Cu4O3 phases only appeared under the same process conditions. The doped elements caused lattice contraction and decreased the thickness of the 1DPC, which was the most important factor affecting the emissivity. The results of the emissivity measurement showed that the single period film thickness of Cu80Ni15Ag5/Ni???Ag-doped Cu4O3 was close to 280 nm, and the number of periods was 2???4. Therefore, the Cu80Ni15Ag5/Ni???Ag-doped Cu4O3 1DPC had good selective infrared properties with an average emissivity of less than 0.1 in the 3???5 ??m band and larger than 0.94 in the 8???14 ??m band; thus, this 1DPC is IP 14 98 160 66 On: Wed 18 May 2022 06:36:21 expected to be used as an infrared sectral modulation material.
Keyword :
Reactive Sputtering Reactive Sputtering Periodic Structure Multilayer Film Periodic Structure Multilayer Film Selective Infrared Radiative Material Selective Infrared Radiative Material
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GB/T 7714 | Li, Yongqing , Wang, Qun , Jin, Xin et al. Structural and Infrared Spectral Modulation Properties of a CuNiAg Alloy/Ni-Ag-Doped Cu4O3 One-Dimensional Photonic Crystal [J]. | JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS , 2022 , 17 (1) : 177-186 . |
MLA | Li, Yongqing et al. "Structural and Infrared Spectral Modulation Properties of a CuNiAg Alloy/Ni-Ag-Doped Cu4O3 One-Dimensional Photonic Crystal" . | JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS 17 . 1 (2022) : 177-186 . |
APA | Li, Yongqing , Wang, Qun , Jin, Xin , Yu, Yunfei . Structural and Infrared Spectral Modulation Properties of a CuNiAg Alloy/Ni-Ag-Doped Cu4O3 One-Dimensional Photonic Crystal . | JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS , 2022 , 17 (1) , 177-186 . |
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Abstract :
In this study, we prepared a streptavidin magnetic bead based on graphene-coated iron nitride magnetic beads (G@FeN-MB) and tried to use it for the enrichment of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The outer shell of our magnetic bead was wrapped with multiple graphene sheets, and there is no report on the application of graphene to the magnetic-bead-coating material. First, the graphene shell of G@FeN-MB was oxidized by a modified Hummer method so as to generate the carboxyl groups required for the coupling of streptavidin (SA) on the surface of the magnetic beads. X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), and transmission electron microscopy (TEM) were used to characterize the oxidized G@FeN-MB (GO@FeN-MB). Streptavidin was then linked to the surface of the GO@FeN-MB by coupling the amino of the streptavidin with the carboxyl on the magnetic beads by carbodiimide method; thus, the streptavidin magnetic beads (SAMBs) were successfully prepared. To prove the practicality of the SAMBs, biotinylated SARS-CoV-2 S1 antibody was linked with it to respectively capture SARS-CoV-2 Spike-protein-coupled polystyrene beads (S-PS) and pseudovirus with S-protein expressed. Microplate reader and fluorescence microscope results show that the SAMBs can effectively enrich viruses. In conclusion, the preparation of SAMBs with G@FeN-MB is feasible and has potential for application in the field of virus enrichment.
Keyword :
graphene graphene streptavidin magnetic beads streptavidin magnetic beads SARS-CoV-2 SARS-CoV-2 virus enrichment virus enrichment
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GB/T 7714 | Li, Jianxing , Wang, Minglian , Jia, Runqing et al. Graphene-Coated Iron Nitride Streptavidin Magnetic Beads: Preparation and Application in SARS-CoV-2 Enrichment [J]. | MAGNETOCHEMISTRY , 2022 , 8 (4) . |
MLA | Li, Jianxing et al. "Graphene-Coated Iron Nitride Streptavidin Magnetic Beads: Preparation and Application in SARS-CoV-2 Enrichment" . | MAGNETOCHEMISTRY 8 . 4 (2022) . |
APA | Li, Jianxing , Wang, Minglian , Jia, Runqing , Ma, Zhuang , Zhang, Xiaoxu , Li, Jintao et al. Graphene-Coated Iron Nitride Streptavidin Magnetic Beads: Preparation and Application in SARS-CoV-2 Enrichment . | MAGNETOCHEMISTRY , 2022 , 8 (4) . |
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Abstract :
Based on Mie scattering theory, fractal theory, the generalized multiparticle Mie model and the attenuated total reflectance infrared spectroscopy method, this paper aimed to explore the influence of different distribution morphologies of semiconductor nanoparticles on their radiation properties. The results revealed that (1) the symmetry and fluctuation amplitude of the scattering direction of the SiC elementary particles, with a diameter of 100 nm, and the cluster particles were related to the wavelength, particle size and agglomeration state. (2) The particle size distribution had a significant effect on the spectral extinction performance of the SiC particles, especially when lambda > 10 mu m, which can be greatly strengthened by increasing the proportion of large-scale particles. (3) The influence of SiC particle clusters on their spectral extinction was directly related to the cluster size and wavelength. When lambda < 10 mu m, small-scale cluster particles showed lower extinction performances; however, the absorption and scattering factors increased with the increase in cluster size while lambda > 10 mu m, and the extinction performance significantly improved. In summary, the quantitative changes in the microscale and structure, as well as the distribution states, had a significant impact on the infrared spectral characteristics of the particles, and we expect to adjust the particle size distribution to obtain desired radiation properties.
Keyword :
Mie scattering theory Mie scattering theory cluster particles cluster particles particle scattering particle scattering generalized multiparticle Mie theory generalized multiparticle Mie theory attenuated total reflectance infrared spectroscopy method attenuated total reflectance infrared spectroscopy method particle agglomeration particle agglomeration elementary particles elementary particles fractal theory fractal theory
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GB/T 7714 | Li, Yanan , Wang, Qun , Wang, Xiaoli et al. Simulation and Testing of the Radiation Performance of SiC Particles with Different Distribution Morphologies [J]. | PHOTONICS , 2022 , 9 (5) . |
MLA | Li, Yanan et al. "Simulation and Testing of the Radiation Performance of SiC Particles with Different Distribution Morphologies" . | PHOTONICS 9 . 5 (2022) . |
APA | Li, Yanan , Wang, Qun , Wang, Xiaoli , Dong, Shikui . Simulation and Testing of the Radiation Performance of SiC Particles with Different Distribution Morphologies . | PHOTONICS , 2022 , 9 (5) . |
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Abstract :
The dielectric constant of CCTO materials can be as high as 10(4), which makes it suitable for use in electronic devices but the high dielectric loss limits its application. In this paper, a series of Sr and Zr co-doped CCTO ceramics having the formula Ca0.8Sr0.2Cu3Ti4-xZrxO12 (x = 0.1, 0.2, 0.3, 0.4) were obtained via a solid-state reaction technique. We force the effect of the Zr content on the phase composition, microstructure, cationic valence states, impedance, and dielectric properties of the as-prepared ceramics to reduce dielectric loss. The results demonstrate that Sr and Zr co-doping increases dielectric constant and reduces dielectric loss simultaneously, and the maximum dielectric constant (1.87 x 10(5), 1 Hz) and minimum dielectric loss (0.43, 10(2) Hz) are obtained when x = 0.3. Mixed Cu+/Cu2+ and Ti3+/Ti4+ valence states are observed to coexist in the co-doped material lattices, which promote dipole polarization, and thereby increase the dielectric constant of the ceramics. The dielectric properties of the materials are analyzed according to the internal barrier layer capacitance model, which elucidates the contributions of the grains and grain boundaries to dielectric performance. The maximum grain boundary resistance (3.7 x 10(5) omega) is obtained for x = 0.3, which contributes toward the minimum dielectric loss (0.43) obtained for this ceramic at a frequency less than 1 kHz. The average grain sizes of the samples decrease with increasing Zr content, which is the primary factor increasing the grain boundary resistance of the co-doped ceramics.
Keyword :
dielectric properties dielectric properties IBLC IBLC CaCu3Ti4O12 (CCTO) CaCu3Ti4O12 (CCTO) co-doped co-doped mixed valence structure mixed valence structure
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GB/T 7714 | Yu, Yunfei , Wang, Qun , Li, Yongqing et al. Sr and Zr Co-Doped CaCu3Ti4O12 Ceramics with Improved Dielectric Properties [J]. | MATERIALS , 2022 , 15 (12) . |
MLA | Yu, Yunfei et al. "Sr and Zr Co-Doped CaCu3Ti4O12 Ceramics with Improved Dielectric Properties" . | MATERIALS 15 . 12 (2022) . |
APA | Yu, Yunfei , Wang, Qun , Li, Yongqing , Rehman, Mehtab Ur , Khan, Waheed Qamar . Sr and Zr Co-Doped CaCu3Ti4O12 Ceramics with Improved Dielectric Properties . | MATERIALS , 2022 , 15 (12) . |
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Abstract :
Photonic crystals can effectively modulate infrared spectral properties. In this paper, a one-dimensional photonic crystal of multilayer Cu/CuO is proposed to achieve selective infrared radiation within atmospheric windows. A multilayer Cu/CuO with a periodic structure was designed via the transfer matrix method and prepared via reactive sputtering. The results of emissivity measurement showed that the Cu/CuO one-dimensional photonic crystals with 2???4 periods and a certain thickness exhibited good infrared-selective properties, with average emissivities of 0.1 and 0.9 at wavelengths of 3???5 and 8???14 ??m, respectively; thus, the Cu/CuO onedimensional photonic crystals have potential applications as infrared spectral modulation materials.
Keyword :
Reactive Sputtering Reactive Sputtering One-Dimensional Photonic Crystal One-Dimensional Photonic Crystal Selective Infrared Radiative Material Selective Infrared Radiative Material
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GB/T 7714 | Li, Yongqing , Wang, Qun . Design and Infrared Spectral Modulation Properties of Cu/CuO One-Dimensional Photonic Crystals [J]. | SCIENCE OF ADVANCED MATERIALS , 2022 , 14 (2) : 372-382 . |
MLA | Li, Yongqing et al. "Design and Infrared Spectral Modulation Properties of Cu/CuO One-Dimensional Photonic Crystals" . | SCIENCE OF ADVANCED MATERIALS 14 . 2 (2022) : 372-382 . |
APA | Li, Yongqing , Wang, Qun . Design and Infrared Spectral Modulation Properties of Cu/CuO One-Dimensional Photonic Crystals . | SCIENCE OF ADVANCED MATERIALS , 2022 , 14 (2) , 372-382 . |
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Abstract :
Double perovskite compounds (DPCs) have gained much more attention due to their versatile character in the fields of electronics and spintronics. Using density functional theory (DFT) we investigated the electronic, magnetic and optical properties of DPC La2BB ' O-6 where B = Cr, Sc and V and B ' = Co, Ni. The electronic band gaps suggest these compounds are half-metallic (HF) semiconductors in the spin-up channel and metallic in the spin-down channel. Magnetic properties suggest these are ferromagnetic in nature, so all DPCs are half-metallic ferromagnetic (HM-FM). Furthermore, the compound La2CrCoO6 shows outstanding electronic and optical properties, so it can be used in optoelectronic/spintronic devices.
Keyword :
DFT DFT double perovskite double perovskite optical conductivity optical conductivity electronic electronic magnetic magnetic
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GB/T 7714 | Rehman, Mehtab Ur , Wang, Qun , Yu, Yunfei . Electronic, Magnetic and Optical Properties of Double Perovskite Compounds: A First Principle Approach [J]. | CRYSTALS , 2022 , 12 (11) . |
MLA | Rehman, Mehtab Ur et al. "Electronic, Magnetic and Optical Properties of Double Perovskite Compounds: A First Principle Approach" . | CRYSTALS 12 . 11 (2022) . |
APA | Rehman, Mehtab Ur , Wang, Qun , Yu, Yunfei . Electronic, Magnetic and Optical Properties of Double Perovskite Compounds: A First Principle Approach . | CRYSTALS , 2022 , 12 (11) . |
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Abstract :
针对工业系统中机械连接的控制需求,设计一种以电磁体和永磁体间的斥力为解锁分离力,永磁体对电磁体铁芯的磁力作为预紧力的电磁永磁互调解锁装置。首先用磁路分析法分析电磁力与永磁力之间的互调原理,然后利用仿真软件分析轭铁关键结构参数对解锁分离力的影响,最后依据研究结论制备了尺寸为45mm×40 mm×40 mm的样机,证明了该装置具有结构简单、功耗低、重量轻、体积小、性能可靠等优点,同时还具有可调控的锁定力、解锁力和分离距离,在机械控制领域中具有很大的应用前景。
Keyword :
电磁永磁互调 电磁永磁互调 有限元分析 有限元分析 磁路 磁路
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GB/T 7714 | 金鑫 , 陈树君 , 郭海霞 et al. 电磁永磁互调解锁装置仿真与设计 [J]. | 微电机 , 2021 , 54 (04) : 16-20 . |
MLA | 金鑫 et al. "电磁永磁互调解锁装置仿真与设计" . | 微电机 54 . 04 (2021) : 16-20 . |
APA | 金鑫 , 陈树君 , 郭海霞 , 丁叁叁 , 张敏 , 唐章宏 et al. 电磁永磁互调解锁装置仿真与设计 . | 微电机 , 2021 , 54 (04) , 16-20 . |
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