In　this　chapter,　we　review　recent　progress　of　using　tellurite　glass　nonlinear　optical　fibers　for　mid-infrared　nonlinear　applications.　First,　we　introduce　various　fabrication　approaches　producing　conventional　solid　core/cladding　tellurite　glass　preforms　and　structured　tellurite　glass　preforms.　Second,　two　technical　difficulties　have　been　found　during　the　early　stage　of　using　small-core　tellurite　glass　fiber　for　generating　nonlinear　supercontinuum　into　mid-infrared　region.　Approaches　such　as　glass　dehydration　and　large-mode-area　fiber　have　been　developed　for　solving　these　problems.　©　2017,　Springer　International　Publishing　AG.