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Author:

Tsui, Po-Hsiang (Tsui, Po-Hsiang.) | Wang, Chiao-Yin (Wang, Chiao-Yin.) | Zhou, Zhuhuang (Zhou, Zhuhuang.) | Wan, Yung-Liang (Wan, Yung-Liang.)

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Scopus SCIE PubMed

Abstract:

Radiofrequency ablation (RFA) is a minimally invasive method for treating tumors. Shear wave elastography (SWE) has been widely applied in evaluating tissue stiffness and final ablation size after RFA. However, the usefulness of periablation SWE imaging in assessing RFA remains unclear. Therefore, this study investigated the correlation between periablation SWE imaging and final ablation size. An in vitro porcine liver model was used for experimental validation (n = 36). During RFA with a power of 50 W, SWE images were collected using a clinical ultrasound system. To evaluate the effects of tissue temperature and gas bubbles during RFA, changes in the ablation temperature were recorded, and image echo patterns were measured using B-mode and ultrasound statistical parametric images. After RFA, the gross pathology of each tissue sample was compared with the region of change in the corresponding periablation SWE image. The experimental results showed that the tissue temperature at the ablation site varied between 70 degrees C and 100 degrees C. Hyperechoic regions and changes were observed in the echo amplitude distribution induced by gas bubbles. Under this condition, the confounding effects (including the temperature increase, tissue stiffness increase, and presence of gas bubbles) resulted in artifacts in the periablation SWE images, and the corresponding region correlated with the estimated final ablation size obtained from the gross pathology (r = 0.8). The findings confirm the feasibility of using periablation SWE imaging in assessing RFA.

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Author Community:

  • [ 1 ] [Tsui, Po-Hsiang]Chang Gung Univ, Dept Med Imaging & Radiol Sci, Coll Med, Taoyuan, Taiwan
  • [ 2 ] [Wang, Chiao-Yin]Chang Gung Univ, Dept Med Imaging & Radiol Sci, Coll Med, Taoyuan, Taiwan
  • [ 3 ] [Wan, Yung-Liang]Chang Gung Univ, Dept Med Imaging & Radiol Sci, Coll Med, Taoyuan, Taiwan
  • [ 4 ] [Tsui, Po-Hsiang]Chang Gung Univ, Inst Radiol Res, Med Imaging Res Ctr, Taoyuan, Taiwan
  • [ 5 ] [Wan, Yung-Liang]Chang Gung Univ, Inst Radiol Res, Med Imaging Res Ctr, Taoyuan, Taiwan
  • [ 6 ] [Tsui, Po-Hsiang]Chang Gung Mem Hosp Linkou, Taoyuan, Taiwan
  • [ 7 ] [Wan, Yung-Liang]Chang Gung Mem Hosp Linkou, Taoyuan, Taiwan
  • [ 8 ] [Tsui, Po-Hsiang]Chang Gung Mem Hosp Linkou, Dept Med Imaging & Intervent, Taoyuan, Taiwan
  • [ 9 ] [Wan, Yung-Liang]Chang Gung Mem Hosp Linkou, Dept Med Imaging & Intervent, Taoyuan, Taiwan
  • [ 10 ] [Wang, Chiao-Yin]Chang Gung Univ, Grad Inst Clin Med Sci, Coll Med, Taoyuan, Taiwan
  • [ 11 ] [Zhou, Zhuhuang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

Reprint Author's Address:

  • [Tsui, Po-Hsiang]Chang Gung Univ, Dept Med Imaging & Radiol Sci, Coll Med, Taoyuan, Taiwan;;[Wan, Yung-Liang]Chang Gung Univ, Dept Med Imaging & Radiol Sci, Coll Med, Taoyuan, Taiwan;;[Tsui, Po-Hsiang]Chang Gung Univ, Inst Radiol Res, Med Imaging Res Ctr, Taoyuan, Taiwan;;[Wan, Yung-Liang]Chang Gung Univ, Inst Radiol Res, Med Imaging Res Ctr, Taoyuan, Taiwan;;[Tsui, Po-Hsiang]Chang Gung Mem Hosp Linkou, Taoyuan, Taiwan;;[Wan, Yung-Liang]Chang Gung Mem Hosp Linkou, Taoyuan, Taiwan;;[Tsui, Po-Hsiang]Chang Gung Mem Hosp Linkou, Dept Med Imaging & Intervent, Taoyuan, Taiwan;;[Wan, Yung-Liang]Chang Gung Mem Hosp Linkou, Dept Med Imaging & Intervent, Taoyuan, Taiwan

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Source :

PLOS ONE

ISSN: 1932-6203

Year: 2016

Issue: 9

Volume: 11

3 . 7 0 0

JCR@2022

ESI Discipline: Multidisciplinary;

ESI HC Threshold:301

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count: 11

SCOPUS Cited Count: 13

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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