Multilateration　measurement　using　laser　trackers　suffers　from　a　cumbersome　solution　method　for　high-precision　measurements.　Errors　are　induced　by　the　self-calibration　routines　of　the　laser　tracker　software.　This　paper　describes　an　optimization　solution　model　for　laser　tracker　multilateration　measurement,　which　effectively　inhibits　the　negative　effect　of　this　self-calibration,　and　further,　analyzes　the　accuracy　of　the　singular　value　decomposition　for　the　described　solution　model.　Experimental　verification　for　the　solution　model　based　on　laser　tracker　and　coordinate　measuring　machine　(CMM)　was　performed.　The　experiment　results　show　that　the　described　optimization　model　for　laser　tracker　multilateration　measurement　has　good　accuracy　control,　and　has　potentially　broad　application　in　the　field　of　laser　tracker　spatial　localization.