Metal-organic　polyhedra　(MOPs)　have　attracted　great　attention　due　to　their　intriguing　structure.　However,　the　applications　of　MOPs　are　severely　hindered　by　two　shortcomings,　namely　low　dispersity　and　poor　stability.　Here　we　report　the　introduction　of　four　MOPs　(constructed　from　dicopper　and　carboxylates)　to　cavity　structured　mesoporous　silica　SBA-16　via　a　double-solvent　strategy　to　overcome　both　shortcomings　simultaneously.　By　judicious　design,　the　dimension　of　MOPs　is　just　between　the　size　of　cavities　and　entrances　of　SBA-16,　MOP　molecules　are　thus　confined　in　the　cavities.　This　leads　to　the　formation　of　isolated　MOPs　with　unusual　dispersion,　making　the　active　sites　highly　accessible.　Hence,　the　adsorption　capacity　on　carbon　dioxide　and　propene　as　well　as　catalytic　performance　on　ring　opening　are　much　superior　to　bulk　MOPs.　More　importantly,　the　structure　and　catalytic　activity　of　MOPs　in　confined　cavities　are　well　preserved　after　exposure　to　humid　atmosphere,　whereas　those　of　bulk　MOPs　are　degraded　seriously.