The　polymethyl　methacrylate-templating　and　polyvinyl　alcohol-protected　reduction　routes　were　adopted　to　prepared　three-dimensionally　ordered　macroporous　(3DOM)　Co3O4　and　its　supported　gold-palladium　alloy　(xAuPd/3DOM　Co3O4,　x　=　0.50-1.99　wt%　and　Au/Pd　mass　ratio　=　1:1)　nanocatalysts.　The　3DOM　Co3O4　supported　Au-Pd　samples　performed　much　better　than　supported　single　Au　or　Pd　samples,　with　the　1.99AuPd/3DOM　Co304　sample　showing　the　best　performance:　the　T-10%,　T-50%,　and　T-90%　(temperatures　required　for　achieving　toluene　conversions　of　10%,　50%,　and　90%)　were　145,　164,　and　168　degrees　C　at　a　space　velocity　of　40,000　mL/(g　h),　respectively.　The　3DOM　Co3O4　supported　Au-Pd　nanocatalysts　also　exhibited　better　catalytic　stability　and　more　moisture-tolerant　ability　than　the　supported　Au　or　Pd　samples　for　toluene　oxidation.　The　apparent　activation　energies　(33-41　kJ/mol)　over　xAuPd/3DOM　Co3O4　were　much　lower　than　those　(52-112　kJ/mol)　over　3DOM　Co3O4　and　supported　single　Au　or　Pd　samples,　with　the　1.99AuPd/3DOM　Co3O4　sample　exhibiting　the　lowest　apparent　activation　energy　(33　kJ/mol).　It　is　concluded　that　better　oxygen　activation　ability　and　stronger　noble　metal-3DOM　Co3O4　interaction　were　responsible　for　the　excellent　catalytic　performance　of　1.99AuPd/3DOM　Co3O4.　(C)　2014　Elsevier　Inc.　All　rights　reserved.