Porous　cube-aggregated　monodisperse　Co3O4　microspheres　and　their　supported　gold　(xAu/Co3O4　microsphere,　x=1.6-7.4wt%)　nanoparticles　(NPs)　were　fabricated　using　the　glycerol-assisted　solvothermal　and　polyvinyl　alcohol-protected　reduction　methods.　Physicochemical　properties　of　the　materials　were　characterized　by　means　of　numerous　analytical　techniques,　and　their　catalytic　activities　were　evaluated　for　the　oxidation　of　toluene　and　CO.　It　is　shown　that　the　cubic　Co3O4　microspheres　were　composed　of　aggregated　cubes　with　a　porous　structure.　The　gold　NPs　with　a　size　of　3.2-3.9nm　were　uniformly　deposited　on　the　surface　of　Co3O4　microspheres.　Among　the　Co3O4　microsphere　and　xAu/Co3O4　microsphere　samples,　the　7.4Au/Co3O4　microspheres　performed　the　best,　giving　T-90%　values　(the　temperature　required　for　achieving　a　CO　or　toluene　conversion　of　90%　at　a　weight　hourly　space　velocity　of　20000mLg(-1)h(-1))　of　-8　and　250　degrees　C　for　CO　and　toluene　oxidation,　respectively.　In　the　case　of　3.0vol%　water　vapor　introduction,　a　positive　effect　on　CO　oxidation　and　a　small　negative　effect　on　toluene　oxidation　were　observed　over　the　7.4Au/Co3O4　microsphere　sample.　The　apparent　activation　energies　obtained　over　the　xAu/Co3O4　microsphere　samples　were　in　the　ranges　of　40.7-53.6kJmol(-1)　for　toluene　oxidation　and　21.6-34.6kJmol(-1)　for　CO　oxidation.　It　is　concluded　that　the　higher　oxygen　adspecies　concentration,　better　low-temperature　reducibility,　and　stronger　interaction　between　gold　NPs　and　Co3O4　as　well　as　the　porous　microspherical　structure　were　responsible　for　the　excellent　catalytic　performance　of　7.4Au/Co3O4　microsphere.