The　thrombus　is　the　inappropriate　activation　of　hemostasis　in　vascular　system.　In　this　paper,　biomechanical　factors　affecting　the　behaviors　of　artery　with　intraluminal　thrombus　were　studies.　Results　indicated　that　heart　rate　and　blood　viscosity　had　strong　impact　on　the　compliance　of　the　stenosis　artery　and　flow　pattern.　The　alteration　in　blood　viscosity　had　stronger　influence　than　cardiac　cycle　on　the　volume　change　of　the　fluid　region　surrounded　by　thrombus.　von　Mises　stress　measured　at　the　thinnest　region　of　the　plaque　had　the　largest　time-averaged　value.　The　alteration　of　these　parameters　could　potentially　lead　to　stress　redistribution　at　intraluminal　thrombus.