The　global　bifurcations　and　multi-pulse　chaotic　dynamics　of　a　simply　supported　honeycomb　sandwich　rectangular　plate　under　combined　parametric　and　transverse　excitations　are　investigated　in　this　paper　for　the　first　time.　The　extended　Melnikov　method　is　generalized　to　investigate　the　multi-pulse　chaotic　dynamics　of　the　non-autonomous　nonlinear　dynamical　system.　The　main　theoretical　results　and　the　formulas　are　obtained　for　the　extended　Melnikov　method　of　the　non-autonomous　nonlinear　dynamical　system.　The　nonlinear　governing　equation　of　the　honeycomb　sandwich　rectangular　plate　is　derived　by　using　the　Hamilton＇s　principle　and　the　Galerkin＇s　approach.　A　two-degree-of-freedom　non-autonomous　nonlinear　equation　of　motion　is　obtained.　It　is　known　that　the　less　simplification　processes　on　the　system　will　result　in　a　better　understanding　of　the　behaviors　of　the　multi-pulse　chaotic　dynamics　for　high-dimensional　nonlinear　systems.　Therefore,　the　extended　Melnikov　method　of　the　non-autonomous　nonlinear　dynamical　system　is　directly　utilized　to　analyze　the　global　bifurcations　and　multi-pulse　chaotic　dynamics　of　the　two-degree-of-freedom　non-autonomous　nonlinear　system　for　the　honeycomb　sandwich　rectangular　plate.　The　theoretical　results　obtained　here　indicate　that　multi-pulse　chaotic　motions　can　occur　in　the　honeycomb　sandwich　rectangular　plate.　Numerical　simulation　is　also　employed　to　find　the　multi-pulse　chaotic　motions　of　the　honeycomb　sandwich　rectangular　plate.　It　also　demonstrates　the　validation　of　the　theoretical　prediction.