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Author:

Xu, Yi-Sheng (Xu, Yi-Sheng.) | Zeng, Cheng-Chu (Zeng, Cheng-Chu.) (Scholars:曾程初) | Jiao, Zi-Guo (Jiao, Zi-Guo.) | Hu, Li-Ming (Hu, Li-Ming.) (Scholars:胡利明) | Zhong, Ru-gang (Zhong, Ru-gang.) (Scholars:钟儒刚)

Indexed by:

Scopus SCIE PubMed

Abstract:

4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by H-1-NMR, C-13-NMR, IR and ESI (or HRMS) spectra. Compounds were screened for possible HIV integrase inhibitory activity.

Keyword:

Aryl diketo acids 4-Oxo-4H-quinolizine-3-carboxylic acid derivatives Mg2+ binding HIV-1 integrase

Author Community:

  • [ 1 ] [Xu, Yi-Sheng]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 2 ] [Zeng, Cheng-Chu]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 3 ] [Jiao, Zi-Guo]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 4 ] [Hu, Li-Ming]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 5 ] [Zhong, Ru-gang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 6 ] [Xu, Yi-Sheng]Chinese Res Inst Environm Sci, Atmospher Chem & Aerosol Res Dept, Beijing 100012, Peoples R China

Reprint Author's Address:

  • 曾程初

    [Zeng, Cheng-Chu]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

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Source :

MOLECULES

ISSN: 1420-3049

Year: 2009

Issue: 2

Volume: 14

Page: 868-883

4 . 6 0 0

JCR@2022

ESI Discipline: CHEMISTRY;

JCR Journal Grade:3

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count: 41

SCOPUS Cited Count: 44

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 7

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