The　purpose　of　this　research　was　to　design　and　realize　a　real-time　tele-monitoring　system　with　multiphysiological　parameters　using　the　Internet.　Both　the　Client/Server　(C/S)　mode　and　Peer-to-Peer　(P2P)　mode　were　used　in　the　system＇s　network　communication.　The　C/S　mode　is　used　to　upload,　retrieve,　and　download　physiological　data.　The　P2P　mode　provides　real-time　tele-monitoring　and　video　chatting　between　doctors　and　patients.　Experiment　results　show　that　P2P　technology　could　efficiently　improve　the　transmission　speed　of　the　physiological　parameters.　This　study　demonstrates　an　effective　method　of　remote　monitoring　of　physiological　parameters　in　real　time.