Abstract:
亚硝胺是一类重要致癌物质,在体内细胞色素P450的作用下经代谢活化生成活泼亲电试剂,导致DNA碱基的烷化损伤最终诱发癌症。因此,P450催化亚硝胺的代谢活化是其致癌过程的关键步骤。
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Year: 2016
Page: 1-1
Language: Chinese
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30 Days PV: 5
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