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Abstract:
The innate anti-HIV-1 factors in human that have been discovered recently not only interact with HIV-1 components, but also have broad protein-protein interactions with other proteins. All these factors form a large network in which some of these proteins with similar structures and related functions may form complexes in order to accomplish specific biologic pathways. This study utilized a network visualizing and analyzing software, Cytoscape, to create a network of 7 proteins (i.e. APOBEC3G, Trim5 alpha, BST-2, CBF-beta, Vif, Gag and Vpu) that are related to HIV-1, and predicted two putative complexes with ClusterViz and MCODE plug-in.
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2014 INTERNATIONAL CONFERENCE ON BIOLOGICAL ENGINEERING AND BIOMEDICAL (BEAB 2014)
Year: 2014
Page: 19-23
Language: English
Cited Count:
WoS CC Cited Count: 2
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 8
Affiliated Colleges: