Photocatalytic　hydrogen　production　from　water　splitting　has　received　considerable　attention　in　recent　years.　The　bottle-neck　issue　for　hydrogen　production　efficiency　is　the　relative　slow　charge　separation　and　efficient　hydrogen　evolution.　Currently,　the　major　strategy　for　developing　catalysts　is　to　anchor　small　noble-metal　cocatalysts　onto　relatively　large　photocatalysts.　In　this　study,　extremely　small　photocatalysts　of　TiO2　quantum　dots　were　loaded　onto　the　low-cost　micro-sized　cocatalysts　of　porous　NiO/NiS2　nanosheets,　promoting　the　rapid　charge　separation　of　photogenerated　electrons　from　small-sized　photocatalysts　to　large-sized　cocatalysts.　The　size　of　cocatalysts　is　three　orders　of　magnitude　larger　than　that　of　photocatalysts.　The　hydrogen　production　of　designed　catalysts　is　similar　to　16　times　higher　than　that　of　pure　TiO2　photocatalysts,　clearly　demonstrating　the　critical　role　of　large-sized　porous　cocatalysts.　Our　game-changing　strategy　provides　a　distinctive　approach　to　design　new　kinds　of　photocatalysts　with　rapid　charge　separation　and　highly　efficient　hydrogen　evolution.