The　metal　organic　framework　derived　materials　(CoFe2O4@NC)　activated　peroxymonosulfate　(PMS)　to　degrade　Norfloxacin　(NOR)　owing　to　the　characteristics　of　high　surface　area　(109.658 m2 g-1)　and　abundant　mesoporous　structure.　The　characterization　results　demonstrated　that　the　optimal　ratio　of　bimetal　and　of　bimetallic　to　organic　ligands　(M/O)　had　good　crystal　structure　and　stability　(Fe/Co = 3:1,　M/O = 2:1).　Moreover,　NOR　(10 mg L-1)　removal　of　98.78%　was　achievable　in　60 min　with　an　optimum　concentration　of　PMS　(0.32 mM)　and　dosage　of　CoFe2O4@NC　(0.1 g L-1).　The　radical　quenching　results　suggested　that　SO4·-,　·OH　and　1O2　functioned　in　the　presence　of　the　system　certificated　by　XPS　spectra.　The　presence　of　Cl-　and　CO32-/HCO3-　promoted　the　catalyst　reaction.　The　recoverability　revealed　high　removal　efficiency　of　NOR　of　93.55%　could　still　be　maintained.　Furthermore,　four　pathways　of　NOR　degradation　were　proposed,　including　dehydroxylation,　defluorination,　quinolone　group　conversion　and　piperazine　ring　transformation,　which　were　attributed　to　the　synergy　of　reactive　oxygen　species.　The　above　results　highlight　that　the　method　is　of　great　significance　to　the　practical　application　of　heterogeneous　catalysts　in　aqueous　solutions.