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Author:

Liu, Bo (Liu, Bo.) (Scholars:刘博) | Zhao, Yelong (Zhao, Yelong.) | Yang, Bin (Yang, Bin.) | Zhao, Shuangtao (Zhao, Shuangtao.) | Gu, Rentao (Gu, Rentao.) | Gahegan, Mark (Gahegan, Mark.)

Indexed by:

EI Scopus SCIE

Abstract:

As an important method to diagnose gastric cancer, gastric pathological sections images (GPSI) are hard and time-consuming to be recognized even by an experienced doctor. An efficient method was designed to detect gastric cancer in magnified (20x) GPSI using deep learning technology. A novel DenseNet architecture was applied, modified with a multistage attention module (MSA-DenseNet). To develop this model focusing on gastric features, a two-stage-input attention module was adopted to select more semantic information of cancer. Moreover, the pretraining process was divided into two steps to improve the effect of the attention mechanism. After training, our method achieved a state-of-the-art performance yielding 0.9947 F1 score and 0.9976 ROC AUC on a test dataset. In line with our expectation in clinical practice, a high recall (0.9929) was produced with high sensitivity to the positive samples. These results indicate that this new model performs better than current artificial detection approaches and its effectiveness is therefore validated in cancer pathological diagnoses.

Keyword:

computer&#8208 assisted diagnosis gastric pathological sections gastric cancer deep learning

Author Community:

  • [ 1 ] [Liu, Bo]Beijing Univ Technol, Sch Software Engn, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 2 ] [Zhao, Yelong]Beijing Univ Technol, Sch Software Engn, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 3 ] [Yang, Bin]Beijing Univ Technol, Sch Software Engn, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 4 ] [Zhao, Shuangtao]Chinese Acad Med Sci & Peking Union Med Coll, Dept Intervent Therapy, Natl Canc Ctr, Canc Hosp, Beijing 100021, Peoples R China
  • [ 5 ] [Gu, Rentao]Beijing Univ Posts & Telecommun, Sch Informat & Commun Engn, Beijing 100876, Peoples R China
  • [ 6 ] [Gahegan, Mark]Univ Auckland, Sch Comp Sci, Auckland 1010, New Zealand

Reprint Author's Address:

  • [Zhao, Shuangtao]Chinese Acad Med Sci & Peking Union Med Coll, Dept Intervent Therapy, Natl Canc Ctr, Canc Hosp, Beijing 100021, Peoples R China

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Source :

CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE

ISSN: 1532-0626

Year: 2021

Issue: 10

Volume: 33

2 . 0 0 0

JCR@2022

ESI Discipline: COMPUTER SCIENCE;

ESI HC Threshold:87

JCR Journal Grade:3

Cited Count:

WoS CC Cited Count: 3

SCOPUS Cited Count: 3

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 10

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