The　18R　and　14H　long-period　stacking　ordered　(LPSO)　phases　were　generally　considered　that　only　the　basal　and　non-basal　slips　and　kink　banding　could　be　activated　during　quasi-state　deformation　at　room　temperature.　Here,　we　confirm　that　the　pyramidal　II　slips　can　also　be　activated　in　the　18R　LPSO　phase　by　quasi-state　nanoindentation　and　in　the　14H　LPSO　phase　by　cold　roll　with　a　rolling　direction　parallel　to　the　(0001)　plane.　Due　to　the　interaction　between　the　Zn6Y8　atomic　clusters　in　the　LPSO　phases　and　the　pyramidal　II　dislocations,　the　pyramidal　II　slips　are　localized　in　the　well-defined　slip　bands　while　the　chemically　ordered　structure　of　Zn6Y8　atomic　clusters　is　disrupted　to　be　disordered.　Additionally,　the　interaction　also　induces　Zn/Y　atoms　segregation　at　the　two　edges　of　the　slip　band.　Our　results　unravel　the　origin　for　the　excellent　room　temperature　plasticity　in　the　LPSO　phases.　©　2021　Elsevier　Ltd