Organic　solvent　nanofiltration　(OSN)　is　a　new　membrane　separation　technology　with　advantage　of　high　efficiency,　environmental　benign　and　energy-saving,　showing　potential　applications　in　recovery　and　treatment　of　organic　solvents.　Herein,　three　OSN　membranes　with　different　wettability　were　fabricated　by　immersing　polysulfone　(PS)　ultrafiltration　membranes　in　PDMS,　PEBAX　and　PVA　solution,　respectively.　The　permeability　of　the　prepared　PDMS/PS,　PEBAX/PS　and　PVA/PS　composite　membranes　to　methanol　(MeOH),　ethanol　(ET),　isopropanol　(IPA),　n-hexanes　and　n-heptane　and　the　nanofiltration　performance　of　the　three　membrans　to　evans　blue　(EB)　methanol　solution　were　explored.　The　results　showed　that　the　flux　of　organic　solvents　was　highly　related　to　the　membrane　surface　wettability　and　molecular　weight,　viscosity,　solubility　parameters　and　polarity　of　organic　solvents.　The　hydrophobic　PDMS/PS　and　PEBAX/PS　composite　membranes　exhibited　the　high　flux　of　58.0　and　72.2L/(m2•h•MPa)　to　organic　solvents,　respectively,　and　the　rejection　of　EB　of　the　hydrophobic　membrane　reached　more　than　90%,　while　the　hydrophilic　PVA/PS　displayed　85%　retention　of　EB　along　with　a　flux　of　57.5L/(m2•h•MPa).　©　2020,　Chemical　Industry　Press.　All　right　reserved.