Al2O3　and　TiO2　nanofluids　based　on　DI-water　with　different　maxing　ratio　were　prepared　by　the　two-step　methods,　and　the　total　volume　concentration　is　0.2%,　respectively.　A　thermal　property　analyzer　(Hot-Disk　2500S)　was　used　to　measure　the　thermal　conductivity　of　hybrid　nanofluids.　The　prepared　hybrid　nanofluids　were　used　to　flow　through　microchannel　heat　sinks　to　test　the　flow　and　convective　heat　transfer　characteristics.　The　hydraulic　diameters　of　microchannels　are　104.35　µm,　and　the　shapes　of　the　channels　are　straight-line　and　broken-line.　The　experiment　results　show　that,　compared　with　DI-water,　the　heat　transfer　performance　of　nanofluids　is　better.　Compared　with　DI-water,　the　convective　heat　transfer　coefficients　of　the　Al2O3　and　TiO2hybrid　nanofluids　with　maxing　ratio　1:　1　in　the　broken-line　microchannel　are　increased　by　9.0%　in　Re=305.　©　2020,　Science　Press.　All　right　reserved.