Pre-ozonation　is　often　used　as　an　effective　method　to　assist　coagulation　in　removing　organic　contaminants.　In　this　study,　a　new　process　that　combining　ozone　(O-3)　with　vacuum　ultraviolet　(VUV/UV)　process　(VUV/UV/O-3)　is　investigated　to　enhance　the　removal　of　organic　matters　in　greywater　from　public　buildings　or　household.　The　influence　of　organic　characteristics　(molecular　weight　distribution,　hydrophobicity,　and　fluorescence)　in　grey　water　on　VUV/UV/O-3　enhanced　coagulation　has　not　been　fully　studied.　Herein,　organic　matters　of　greywater　were　separated　and　classified,　and　fates　of　organic　fractions　by　VUV/UV/O-3　enhanced　coagulation　were　clarified.　Greywater　contains　tryptophan-like　and　tyrosine-like　proteins,　and　terrestrially　derived　humic-like　substances.　The　highest　UV254,　LAS,　DOC　and　CODCr　removal　efficiency　from　greywater　could　reach　up　to　47.54%,　58.92%,　17.96%　and　15.76%　in　VUV/UV/O-3　enhanced　coagulation,　respectively.　The　removal　efficiency　of　tryptophanlike　and　tyrosine-like　in　filtrates　of　varied　molecular　weight　ranges　by　VUV/UV/O-3　enhanced　coagulation　was　93.59%-98.13%　and　89.86%-95.53%,　respectively.　VUV/UV/O-3　enhanced　coagulation　was　effective　for　the　removal　of　bio-polymers,　humic　substances　and　low　molecular　weight　acid　＜=&　nbsp;30　kDa,　while　it　was　insignificant　for　that　of　0.22　mu　m　100　kDa.　Particle　size　of　flocs　increased　significantly　in　filtrates　obtained　from　increasing　membrane　pore　size,　indicating　that　macromolecular　organic　matter　was　more　likely　to　form　flocs.　Finally,　the　VUV/UV/O-3　could　improve　coagulation　on　the　removal　of　varied　organic　pollutants　and　improve　sedimentation　by　changing　the　flaky　flocs　to　dense　ones.　Therefore,　the　results　demonstrate　VUV/UV/O-3　is　an　effective　pre　oxidation　method　to　enhance　the　effect　of　coagulation　on　greywater　treatment.