The　transfer-purge　chamber　is　an　operation　room　for　nuclear　fuel　transport　and　purging　in　a　nuclear　power　plant,　which　has　a　demand　for　structural　reliability　and　radiation　protection.　The　transfer-purge　chamber　has　features　such　as　large　curvature,　heavy　concrete,　long　overhang,　and　irregular　cross-sections,　and　it　is　constructed　of　double　steel　plates　reinforced　concrete　(SC)　structure.　This　study　performed　shaking　table　tests　for　a　1:4.5　scale　model　of　the　transfer-purge　chamber.　Three　sets　of　ground　motions　were　input　in　the　scale　model　in　the　horizontal　and　vertical　directions　to　study　its　structural　reliability　and　seismic　performance.　Acceleration　response　and　strain　response　of　the　structure　were　analyzed　to　evaluate　the　dynamic　characteristics　of　the　transfer-purge　chamber　under　the　ground　motion.　The　results　show　that　the　transfer-purge　chamber　has　great　stiffness　and　short　periods.　The　periods　slightly　increase　with　the　rise　of　intensity　of　seismic　ground　motions.　Under　the　excitation　of　ground　motions,　the　dynamic　response　of　the　transfer-purge　chamber　is　slight.　No　obvious　deformation　or　damage　occurred　on　the　transfer-purge　chamber,　and　cracking　in　concrete　or　buckling　on　steel　plate　did　not　appear.　The　transfer-purge　chamber　has　excellent　seismic　performance,　and　it　is　sufficiently　safe　and　reliable　from　a　structural　perspective.