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Author:

Zhang, Meng (Zhang, Meng.) | Cheng, Yanyan (Cheng, Yanyan.) | Liu, Hongxing (Liu, Hongxing.) | Nan, Qun (Nan, Qun.) (Scholars:南群)

Indexed by:

Scopus SCIE

Abstract:

OBJECTIVE: To cure atrial fibrillation, the maximum ablation depth (>= 50 degrees C) should exceed the myocardial thickness to achieve the effect of transmural ablation. The blood flow of pulmonary vein in the endocardium can cause the change in the myocardial temperature distribution. Therefore, the study investigated the effect of different pulmonary vein blood flow velocities on the endocardial microwave ablation. METHODS: The finite element model of the endocardial microwave ablation of pulmonary vein was simulated by electromagnetic thermal flow coupling. The ablation power was 30 W and the ablation time was within 30 s. The blood flow in the coupling of fluid mechanics equation and heat transfer equation results in the heat damage. Furthermore, the cause of the different lesion dimensions is the blood flow velocity. The flow velocities were set as 0, 0.02, 0.05, 0.07, 0.12, 0.16, 0.20, 0.25 and 0.30 m/s. RESULTS: When the flow velocities were 0, 0.02, 0.05, 0.07, 0.12, 0.16, 0.20, 0.25 and 0.30 m/s, the maximum ablation depth were 6.00, 5.56, 5.16, 5.12, 5.04, 5.01, 4.98, 4.96 and 4.94 mm, respectively; the maximum ablation width were 12.53, 9.63, 9.23, 9.16, 9.07, 9.05, 8.94, 8.91 and 8.90 mm, respectively; the maximum ablation length were 12.00, 11.61, 8.98, 8.59, 8.37, 8.23, 8.16, 8.06 and 8.04 mm respectively. To achieve transmural ablation, the time was 3, 3, 3, 3, 3, 4, 4, 4, 4 s, respectively when the myocardial thickness was 2 mm; the time was 7, 8, 8, 8, 9, 9, 9, 9, 9 s, respectively when 3 mm; the time was 15, 16, 18, 19, 19, 20, 20, 20, 20 s, respectively when 4 mm. CONCLUSIONS: When the velocity increases from 0 m/s to 0.3 m/s, the microwave lesion depth decreases by 1.06 mm. To achieve transmural ablation, when the myocardial thickness is 2 mm, 3 and 4 s should be taken when the velocity is 0-0.12 and 0.12-0.30 m/s, respectively; when the myocardial thickness is 3 mm, 7, 8 and 9 s should be taken when 0, 0-0.07 and 0.07-0.30 m/s respectively; when the myocardial thickness is 4 mm, 15, 16, 18, 19, 20 s should be taken when 0, 0-0.02, 0.02-0.05, 0.05-0.12, 0.12 m/s-0.30 m/s.

Keyword:

numerical simulation Atrial fibrillation microwave ablation blood flow velocity pulmonary vein

Author Community:

  • [ 1 ] [Zhang, Meng]Beijing Univ Technol, Fac Environm & Life Sci, Coll Life Sci & Chem, Beijing 100124, Peoples R China
  • [ 2 ] [Cheng, Yanyan]Beijing Univ Technol, Fac Environm & Life Sci, Coll Life Sci & Chem, Beijing 100124, Peoples R China
  • [ 3 ] [Liu, Hongxing]Beijing Univ Technol, Fac Environm & Life Sci, Coll Life Sci & Chem, Beijing 100124, Peoples R China
  • [ 4 ] [Nan, Qun]Beijing Univ Technol, Fac Environm & Life Sci, Coll Life Sci & Chem, Beijing 100124, Peoples R China

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Source :

TECHNOLOGY AND HEALTH CARE

ISSN: 0928-7329

Year: 2022

Issue: 1

Volume: 30

Page: 29-41

1 . 6

JCR@2022

1 . 6 0 0

JCR@2022

ESI Discipline: MOLECULAR BIOLOGY & GENETICS;

ESI HC Threshold:72

JCR Journal Grade:4

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 10

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