Maintaining　high　activity　during　prolonged　catalysis　is　always　the　pursuit　in　catalytic　degradation　of　organic　pollutants.　For　indoor　formaldehyde　(HCHO)　degradation,　the　accumulation　of　intermediates　is　the　major　factor　limiting　the　conversion　of　HCHO　to　final　product　CO2　(HCHO-to-CO2　conversion)　and　long-lasting　catalysis.　Herein,　a　three-dimensional　radialized　nanostructure　catalyst　self-assembled　by　MnOOH/MnO2　nanosheets　anchored　with　Pt　single　atoms　(PtSA-MnOOH/MnO2　with　a　trace　platinum　loading　amount　of　0.09%)　is　developed　by　thermally　assisted　two-step　electrochemical　method,　which　achieves　enhanced　CO2　production　in　catalytic　HCHO　degradation　at　the　room　temperature　by　the　collaborative　action　of　active　hydroxyl　(OH*)　and　active　oxygen　species　(O2*).　By　boosting　intermediates’　decomposing,　the　catalyst　implements　real-time　HCHO-to-CO2　conversion　(∼85.7%)　and　long-term　continuous　HCHO　removal　(∼98%)　during　100　h　in　a　15　ppm　HCHO　atmosphere　at　25　°C　under　a　weight　hourly　space　velocity　of　30000　mL/gcath.　Density　functional　theory　calculation　shows　that　the　formation　energy　of　O2*　from　O2　over　PtSA-MnOOH/MnO2　is　nearly　half　lower　than　that　over　Pt-MnO2　catalyst.　And　decomposing　accumulated　intermediates　gives　the　credit　to　OH*　species　sustainably　generated　by　the　combined　action　of　MnOOH　and　O2*.　The　synergistic　action　between　PtSA　and　MnOOH　contributes　to　the　continuous　production　of　O2*　and　OH*　for　enhancing　CO2　production　in　indoor　catalytic　formaldehyde　degradation.　©　2022