In　this　paper,　the　FEM　and　MD　method　are　used　to　establish　macro　and　nano　cutting　model　of　OFHC　copper,　and　the　cutting　force,　cutting　stress　and　subsurface　deformation　and　phase　change　are　compared　and　analyzed　under　the　macro　cutting　depth　(0.2mm,　0.3mm,　0.4mm)　and　nano　cutting　depth　(0.8nm,　1.2nm,　1.6nm).　Meanwhile,　experiments　are　used　to　verify　the　simulated　cutting　force.　The　conclusions　are　below:　The　change　trends　of　macro　and　nano　cutting　force　are　similar,　and　the　ratios　of　the　cutting　forces　in　x　and　y　directions　at　different　cutting　depths　are　similar.　In　addition,　there　are　lateral　chip　both　in　the　macro　and　nano　cutting　processes,　showing　a　high　degree　of　consistency.　However,　the　nano　cutting　stress　reached　25　times　of　that　in　the　macro　state.　Then　it　was　found　that　the　area　of　unrecoverable　plastic　deformation　on　the　surface　increased　with　the　increase　of　the　cutting　depth　during　the　macro　cutting　process,　but　the　existence　depth　of　pure　plastic　deformation　remained　unchanged　within　0.05mm.　Although　in　the　nano　cutting　process,　the　proportion　of　FCC　crystals　converted　to　HCP　crystals　remains　unchanged　as　the　cutting　depth　increases,　but　the　existence　range　is　increasing.　Finally,　the　amplitude　and　change　trend　of　experimental　and　the　simulated　cutting　force　are　highly　consistent,　which　verifying　the　rationality　of　the　macro　simulated　cutting　model.　©　IMechE　2022.