Flexible　strain　sensors　have　been　improved　in　sensing　performance　with　the　assistance　of　materials　design,　novel　manufacturing,　and　microstructure　fabrication.　In　this　study,　graphene　was　efficiently　dispersed　in　ethanol　and　then　re-dispersed　into　silicon　rubber　(SR)　matrix,　functioning　as　a　flexible　strain　resistance　sensor　(FSRS)　with　functional　macrostructure　and　modified　microstructure　to　further　improve　the　sensitivity.　A　stable　dispersion　of　graphene　was　obtained　in　an　ultrasound-aided　ball　milling　process,　where　absolute　ethanol　was　selected　as　the　solvent　and　sodium　dodecyl　sulfonate　as　the　surfactant.　Graphene-filled　conductive　SR　was　embedded　in　the　polydimethylsiloxane　matrix　as　a　conductive　sensing　layer,　and　the　high　sensing　performance　(GF　=　25　+/-　2)　was　achieved　using　a　spiral　printed.　Micropores　with　an　optimized　interspacing　of　10　mm　were　further　introduced　into　the　spiral　CSM,　and　the　results　presented　a　significant　improved　sensitivity　(GF　=　51　+/-　4)　of　the　fabricated　FSRS　under　a　working　strain　(20%-30%)　and　cyclic　test　(＞10(4)　cycles).　The　FRSR　was　sensitive　enough　to　monitor　various　movements　of　single　and　multi-joints　of　human　body　and　identify　the　rhythm　of　music　sound,　which　exhibited　its　potential　application　as　a　wearable　flexible　sensor.