Membrane　filtration　technology　has　attracted　extensive　attention　in　academia　and　industry　due　to　its　advantages　of　eco-friendliness　related　to　environmental　protection　and　high　efficiency.　Polyamide　thin-film　composite　nanofiltration　(PA　TFC　NF)　membranes　have　been　widely　used　due　to　their　high　separation　performance.　Non-acid-resistant　PA　TFC　NF　membranes　face　tremendous　challenges　in　an　acidic　environment.　Novel　and　relatively　acid-resistant　polysulfonamide-based　and　triazine-based　TFC　NF　membranes　have　been　developed,　but　these　have　a　serious　trade-off　in　terms　of　permeability　and　selectivity.　Hence,　how　to　improve　acid　resistance　of　TFC　NF　membranes　and　their　separation　performance　in　acidic　environments　is　a　pivotal　issue　for　the　design　and　preparation　of　these　membranes.　This　review　first　highlights　current　strategies　for　improving　the　acid　resistance　of　PA　TFC　NF　membranes　by　regulating　the　composition　and　structure　of　the　separation　layer　of　the　membrane　performed　by　manipulating　and　optimizing　the　construction　method　and　then　summarizes　the　separation　performances　of　these　acid-resistant　TFC　NF　membranes　in　acidic　environments,　as　studied　in　recent　years.