Evaluation and bioparticle density correlation analysis of extended gate HEMT sensors for biological detection from microscopic view - Details

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Abstract：

In　this　letter,　we　focus　on　the　relationship　between　modification　bioparticle　density　(N)　and　biological　regulation　ability　in　extended　gate　HEMT　(EG-HEMT)　biosensors.　By　analyzing,　we　demonstrate　that　under　the　same　gate　electrodes　size　(S　(g))　and　concentration,　N　is　exponentially　related　to　the　area　of　sensing　regions　(y)　and　has　fixed　exponential　magnification　-0.65　+/-　0.05.　This　formula　had　been　demonstrated　to　have　perfect　universality　when　testing　protein　and　small　molecules.　Finally,　we　apply　N　to　the　structural　design　of　EG-HEMT　biosensors　and　projected　that　10　y　structure　has　both　high　biological　regulation　ability　of　biosensors　and　efficient　utility　of　chips.

Keyword：

biological detection extended gate HEMT biosensor bioparticle density

Author Community：

[ 1 ] [Cui, Ning]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 2 ] [Xu, Mengke]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 3 ] [Guan, Min]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 4 ] [Liu, Xingfang]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 5 ] [Zeng, Yiping]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 6 ] [Zhang, Yang]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China
[ 7 ] [Cui, Ning]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 8 ] [Xu, Mengke]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 9 ] [Guan, Min]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 10 ] [Liu, Xingfang]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 11 ] [Zeng, Yiping]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 12 ] [Zhang, Yang]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China
[ 13 ] [Cui, Ning]Beijing Univ Technol, Key Lab Optoelect Technol, Minist Educ, Beijing 100124, Peoples R China

Reprint Author's Address：

[Cui, Ning]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China;;[Guan, Min]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China;;[Zeng, Yiping]Chinese Acad Sci, Inst Semicond, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Beijing 100083, Peoples R China;;[Cui, Ning]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China;;[Guan, Min]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China;;[Zeng, Yiping]Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China;;[Cui, Ning]Beijing Univ Technol, Key Lab Optoelect Technol, Minist Educ, Beijing 100124, Peoples R China;;

Email：

ncui@bjut.edu.cn |
guanmin@semi.ac.cn |
ypzeng@semi.ac.cn

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Source ：

APPLIED PHYSICS EXPRESS

ISSN： 1882-0778

Year： 2023

Issue： 1

Volume： 16

2 . 3 0 0

JCR@2022

ESI Discipline： PHYSICS;

ESI HC Threshold：17

Cited Count：

WoS CC Cited Count： 1

SCOPUS Cited Count： 1

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 9

Affiliated Colleges：

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