A　method　of　improving　the　oxidation　resistance　of　Cantor　alloy　through　microstructure　tailoring　was　revealed.　Samples　with　distinctive　microstructures　were　achieved　by　different　annealing　treatments　on　the　cold-rolled　Cantor　alloy.　Oxidation　test　was　then　carried　out　on　the　various　annealed　samples　at　800　degrees　C　for　24　h　in　air.　The　oxidation　behavior　was　evaluated　in　terms　of　oxidation　rate,　surface　and　cross-section　microstructure　characterization.　Although　stratified　oxide　layers　including　outer　Mn2O3　and　inner　Cr2O3　were　observed　in　all　the　annealed　samples,　the　thickness　of　Mn2O3　and　Cr2O3　layers　was　different.　Also,　the　samples　exhibited　different　oxidation　rates.　The　results　indicate　that　the　oxidation　resistance　of　various　annealed　samples　is　closely　related　with　grain　size　as　well　as　twin　density.