To　obtain　the　sensitivity　of　tissue　characteristics　in　the　temperature　field　of　microwave　ablation　on　lung　tissue,　the　finite　element　method　(FEM)　was　used　to　establish　the　calculation　model　of　microwave　ablation　on　lung　tissue,　the　electromagnetic　field　coupled　with　temperature　field.　The　sensitivity　of　electrical　conductivity　(σ),　relative　permittivity　(ε),　thermal　conductivity　(k),　density　(ρ),　specific　heat　capacity　(Cp)　and　blood　perfusion　rate　(ωb)　were　obtained　based　on　Morris　method.　Four　levels　for　each　of　the　six　parameters　(σ,　ε,　k,　ρ,　Cp,　and　ωb)　were　set　to　obtain　the　ablation　area　and　central　temperature　of　microwave　ablation　of　lung　tissue　at　50　W　and　300　s　in　2D　model.　The　sensitivity　of　ablation　area　and　ablation　shape　was　analyzed　based　on　Morris　method.　Results　show　that　blood　perfusion　rate,　relative　permittivity　and　electrical　conductivity　have　a　great　influence　on　the　ablation　area　and　shape　of　microwave　ablation　of　lung　tissue.　©　2023,　Editorial　Department　of　Journal　of　Beijing　University　of　Technology.　All　right　reserved.