Non-thermal　plasma　(NTP)　is　considered　to　be　a　promising　technology　for　the　removal　of　volatile　organic　compounds;　however,　its　application　is　limited　by　low　CO2　selectivity　and　undesirable　by-products.　To　overcome　these　issues,　this　paper　discusses　the　degradation　of　chlorobenzene　(CB)　in　systems　of　NTP　coupled　with　catalysts,　and　the　influence　of　catalyst　locations　in　the　NTP　was　investigated.　In　addition,　the　interaction　between　plasma　and　catalyst　was　also　explored.　The　results　indicated　that　the　degradability　of　CB　was　remarkably　improved　through　the　combination　of　NTP　with　catalysts,　and　the　formation　of　ozone　was　effectively　inhibited.　The　degradation　efficiency　increased　from　33.9%　to　79.6%　at　14　kV　in　the　NTP-catalytic　system,　while　the　ozone　concentration　decreased　from　437　to　237　mg　m−3,　and　the　degradation　efficiency　of　in　plasma　catalysis　(IPC)　systems　was　superior　to　that　of　the　post　plasma　catalysis　system,　while　the　inhibition　ability　of　ozone　exhibited　an　opposing　trend.　In　the　IPC　system,　the　degradation　efficiency　was　87.7%　at　14　kV,　while　the　ozone　concentration　was　151　mg　m−3.　Besides,　the　plasma　did　not　destroy　the　pore　structure　and　crystal　structure　of　the　catalyst,　but　affected　the　surface　morphology　and　redox　performance　of　the　catalyst.　Thus,　NTP　coupled　catalytic　system　could　improve　the　degradation　performance　of　CB.　Furthermore,　the　plasma　discharge　characteristics　played　a　major　role　in　the　NTP　synergistic　catalytic　degradation　of　CB.　Finally,　based　on　the　experiment　analysis　results,　the　general　reaction　mechanism　of　CB　degradation　in　an　IPC　reaction　system　was　proposed.　©　2023　Hefei　Institutes　of　Physical　Science,　Chinese　Academy　of　Sciences　and　IOP　Publishing