The　nitrogen-doping　carbon　nanotube　modified　polyethersulfone　membrane　(NCNT@PES)　was　prepared　by　vacuum-assisted　filtration.　The　catalytic　activity　and　anti-fouling　capacity　of　NCNT@PES/peroxymonosulfate　(PMS)　system　were　both　systematically　investigated.　Selecting　ethylenediamine　tetra(methylene　phosphonic　acid)　(EDTMP)　as　a　target　phosphonate,　the　NCNT@PES/PMS　system　degraded　almost　100%　of　EDTMP,　and　about　60%　of　the　total　phosphorus　(TP)　in　EDTMP　could　be　transformed　into　orthophosphate　(PO43-)　within　1　min.　Scavenger　experiments　and　electron　paramagnetic　resonance　(EPR)　technique　verified　that　the　surface　-bound　radicals　were　mainly　contributed　the　degradation　and　transformation　of　EDTMP　in　the　NCNT@PES/　PMS　system.　The　presence　of　HCO3　-,　SO42-and　NOM　weakened　the　catalytic　reactions,　nevertheless,　the　NCNT@PES/PMS　system　still　showed　considerable　effectiveness　on　the　transformation　of　EDTMP　in　real　sewage　effluent.　Moreover,　the　anti-fouling　experiment　proved　that　NCNT@PES/PMS　system　were　superior　on　the　removal　of　fluorescent　components　in　the　real　sewage　effluent,　and　their　removal　rates　for　the　dissolved　organic　matter　(DOC)　and　UV　absorbance　at　254　nm　(UV254)　were　also　improved.　During　the　filtration　cycles,　the　NCNT@PES/PMS　system　mitigated　the　membrane　fouling　significantly,　which　had　been　verified　by　the　slower　decline　of　normalized　flux,　less　ultrapure　water　flux　loss　rates　and　higher　ultrapure　water　flux　recovery　rates.　This　study　provided　a　novel　but　simple　way　for　effective　EDTMP　decontamination,　at　the　same　time,　confirmed　the　potential　of　NCNT@PES　membrane　coupled　with　PMS　activation　on　anti-fouling　and　water　purification　ability.