Supported　V2O5@AC　catalysts　synthesized　under　microwave　assistance　were　applied　for　selective　catalytic　reduction　of　NO　by　NH3　(NH3-SCR).　The　activity　evaluation　demonstrated　that　introducing　microwaves　during　the　impregnation　could　significantly　improve　the　deNO(x)　performance　of　V2O5@AC　catalysts,　of　which　3V(2)O(5)@AC-300　achieves　the　highest　deNO(x)　activity　at　low　temperature.　Several　comprehensive　characterization　methods　including　SEM,　H-2-TPR,　Raman,　EPR,　and　XPS　manifested　that　microwaves　induce　the　high　dispersion　of　V2O5　species　and　more　exposed　active　sites.　Additionally,　3V(2)O(5)@AC-300　exhibits　excellent　redox　properties　and　abundant　surface　chemisorbed　oxygen　species,　which　may　be　due　to　the　strong　coupling　interaction　induced　by　microwaves　between　activated　carbon　and　vanadium　species,　thereby　creating　more　coordination-unsaturated　V　species　and　defects.　DFT　calculations　further　verified　that　oxygen　vacancy　doping　could　greatly　promote　the　adsorption　and　activation　of　reactants,　which　is　beneficial　to　SCR　activity.　Moreover,　3V(2)O(5)@AC-300　possesses　a　larger　adsorption　capacity　for　NH3　than　3V(2)O(5)@AC,　indicating　that　microwave　irradiation　could　effectively　modulate　the　adsorption　sites　of　reactants　on　catalysts,　especially　Lewis　acid　sites.　In　situ　DRIFTS　results　revealed　a　high　amount　of　adsorbed　NO2　and　monodentate　nitrate　species,　due　to　abundant　oxygen　vacancies,　were　formed　in　3V(2)O(5)@AC-300,　leading　to　the　acceleration　of　the　SCR　process.