The　aging　behavior　of　asphalt　binder　in　service　is　complex.　The　accelerated　aging　methods　commonly　used　in　the　laboratory　are　difficult　to　reproduce　the　aging　behavior　of　asphalt　binder　in　service.　The　purpose　of　this　study　is　to　develop　a　method　for　predicting　the　properties　of　asphalt　binder　in　service.　First,　a　multi-factor　accelerating　(MFA)　aging　method　was　developed　to　accelerate　the　aging　of　asphalt　binder.　Multi-scale　characterization　and　correlation　analysis　were　conducted　on　the　MFA-aged　asphalt　binder.　Then,　the　evaluation　index　of　MFA　aging　was　defined,　which　was　used　to　establish　the　prediction　equation　for　asphalt　binder　aging.　Finally,　the　time　correlation　between　field　aging,　pressure　aging　vessel　(PAV)　aging　and　MFA　aging　was　constructed　separately.　The　results　show　that　accelerated　aging　of　asphalt　binder　at　atmospheric　pressure　and　service　temperature　can　be　achieved　by　the　coupled　effect　of　temperature,　ultraviolet　light　and　rain.　After　5-day　MFA　aging,　the　Glover　-Rowe　(G-R)　parameter,　an　index　for　evaluating　the　cracking　resistance　of　asphalt　binder,　was　increased　by　308%.　The　carbonyl　index,　an　index　for　evaluating　the　content　of　chemical　functional　groups　of　asphalt　binder,　was　increased　by　67%.　The　correlation　between　the　G-R　parameter　and　the　carbonyl　index　was　linear,　and　the　goodness-of-fit　was　greater　than　0.9.　The　carbonyl　index　as　a　key　chemical　index　may　reflect　the　macroscopic　properties　of　asphalt　binder.　The　prediction　equation　for　aging　was　established　based　on　the　carbonyl　index　of　field-aged　asphalt　binder　in　Beijing,　with　reliability　greater　than　0.98.　PAV　aging　for　20　h　was　equivalent　to　1.35　years　of　asphalt　binder　service　in　Beijing.　MFA　aging　method　can　better　predict　the　aging　time　in　the　field.　The　prediction　accuracy　was　97.2%,　which　was　4.9%　higher　compared　to　that　of　PAV　aging.　MFA　aging　for　5　days　was　equivalent　to　about　2　years　of　asphalt　binder　service　in　Beijing.