It　is　possible　to　remove　volatile　organic　compounds　containing　chlorine　(CVOCs,　such　as　chlorobenzene)　in　a　single　device　designed　for　selective　catalytic　reduction　of　NOx　with　NH3　for　the　industries　containing　CVOCs　and　NOx.　Breaking　the　efficiency-selectivity　trade-off　in　chlorobenzene　oxidation　remains　a　major　challenge　due　to　the　conjugation　of　halogen　atoms　with　the　benzene　ring　and　the　reducing　nature　of　NH3.　A　stepwise　synthesis　strategy　is　demontrated　to　disperse　dual　Ru/Cu　Lewis　acid　sites　outside　and　inside　the　zeolite　channel.　Under　the　confinement　of　zeolite,　the　Ru4+　Lewis　acid　site　on　the　external　surface　of　the　zeolite　promotes　chlorobenzene　oxidation　by　weakening　the　p-&　pi;　conjugate　structure　of　Cl　and　benzene　ring,　while　the　Cu2+　Lewis　acid　site　within　the　internal　channel　converts　NOx　and　NH3　to　N-2.　The　mutual　interference　between　catalytic　oxidation　and　reduction　is　successfully　avoided.　Therefore,　the　low　toxic　CO2　and　HCl　selectivity　experience　a　considerable　increase　from　21%　to　86%,　and　from　51%　to　94%　with　91%　conversion　of　chlorobenzene,　while　maintaining　excellent　elimination　performance　for　NO　(with　N-2　selectivity　exceeding　90%).　The　incorporation　of　separated　active　sites　and　reaction　spaces　into　the　design　may　offer　potentials　for　other　energy　and　environmental　applications.