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Author:

Wang, Qian (Wang, Qian.) | Lai, Ming-Wei (Lai, Ming-Wei.) | Bin, Guangyu (Bin, Guangyu.) | Ding, Qiying (Ding, Qiying.) | Wu, Shuicai (Wu, Shuicai.) | Zhou, Zhuhuang (Zhou, Zhuhuang.) | Tsui, Po-Hsiang (Tsui, Po-Hsiang.)

Indexed by:

EI Scopus SCIE

Abstract:

The evaluation of pediatric hepatic steatosis and early detection of fatty liver in children are of critical importance. In this paper, a deep learning model based on the convolutional neural network (CNN) of ultrasound backscattered signals, multi-branch residual network (MBR-Net), was proposed for characterizing pediatric hepatic steatosis. The MBR-Net was composed of three convolutional branches. Each branch used different sizes of convolution blocks to enhance the capability of local feature acquisition, and leveraged the residual mechanism with skip connections to guide the network to effectively capture features. A total of 393 frames of ultrasound backscattered signals collected from 131 children were included in the experiments. The hepatic steatosis index was used as the reference standard for diagnosing the steatosis grade, G0-G3. The ultrasound backscattered signals within the liver region of interests (ROIs) were normalized and augmented using a sliding gate method. The gated ROI signals were randomly divided into training, validation, and test sets with the ratio of 8:1:1. The area under the operating characteristic curve (AUC), accuracy (ACC), sensitivity (SEN), and specificity (SPE) were used as the evaluation metrics. Experimental results showed that the MBR-Net yields AUCs for diagnosing pediatric hepatic steatosis grade & GE;G1, & GE;G2, and & GE;G3 of 0.94 (ACC: 93.65%; SEN: 89.79%; SPE: 84.48%), 0.93 (ACC: 90.48%; SEN: 87.75%; SPE: 82.65%), and 0.93 (ACC: 87.76%; SEN: 84.84%; SPE: 86.55%), respectively, which were superior to the conventional one-branch CNNs without residual mechanisms. The proposed MBR-Net can be used as a new deep learning method for ultrasound backscattered signal analysis to characterize pediatric hepatic steatosis.

Keyword:

Convolutional neural network Pediatric hepatic steatosis Ultrasound tissue characterization Deep learning Ultrasound backscattered signal

Author Community:

  • [ 1 ] [Wang, Qian]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 2 ] [Bin, Guangyu]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 3 ] [Wu, Shuicai]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 4 ] [Zhou, Zhuhuang]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing, Peoples R China
  • [ 5 ] [Lai, Ming-Wei]Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Chang Gung Childrens Med Ctr,Dept Pediat,Div Pedia, Taoyuan, Taiwan
  • [ 6 ] [Lai, Ming-Wei]Chang Gung Mem Hosp, Liver Res Ctr, Taoyuan, Taiwan
  • [ 7 ] [Ding, Qiying]Beijing Univ Technol, BJUT Hosp, Dept Ultrasound, Beijing, Peoples R China
  • [ 8 ] [Tsui, Po-Hsiang]Chang Gung Univ, Coll Med, Dept Med Imaging & Radiol Sci, Taoyuan, Taiwan
  • [ 9 ] [Tsui, Po-Hsiang]Chang Gung Univ, Inst Radiol Res, Taoyuan, Taiwan
  • [ 10 ] [Tsui, Po-Hsiang]chang Gung Mem Hosp Linkou, Dept Pediat, Div Pediat Gastroenterol, Taoyuan, Taiwan

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Source :

ULTRASONICS

ISSN: 0041-624X

Year: 2023

Volume: 135

4 . 2 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:14

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 9

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