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Author:

高靓 (高靓.) | 李函 (李函.) | 高学云 (高学云.)

Indexed by:

incoPat zhihuiya

Abstract:

本发明提供了一种特异性识别循环肿瘤细胞(CTC)膜蛋白的多肽‑金属团簇探针及其在定量检测中的应用,属于医学检测技术领域。本发明制备一种多肽修饰的金属团簇探针,含有金属团簇核与目标细胞膜蛋白特异性结合的靶向肽。制备的多肽‑金属团簇探针靶向CTC表达的膜蛋白,并利用激光烧蚀电感耦合等离子体质谱技术对临床肿瘤患者外周血液CTC目标膜蛋白进行快速、精准的原位定量分析,从而对临床肿瘤患者的肿瘤侵袭转移行为、分级及预后提供重要参考。

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Patent Info :

Type: 发明申请

Patent No.: CN202111403443.1

Filing Date: 2021-11-24

Publication Date: 2022-03-01

Pub. No.: CN114106098A

Applicants: 北京工业大学

Legal Status: 实质审查

Cited Count:

WoS CC Cited Count: 0

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 6

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