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Author:

曾毅 (曾毅.) | 葛玉洋 (葛玉洋.) | 周志祥 (周志祥.) (Scholars:周志祥) | 滕智平 (滕智平.) | 周玉柏 (周玉柏.)

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incoPat zhihuiya

Abstract:

本发明“一种评估细胞因子对EBV‑LMP2特异性CTL免疫增强效果的实时监测体系”,属于细胞体外培养领域。所述实时监测体系可实时连续动态监测IL‑2和IL‑21对T细胞介导的细胞毒性的免疫增强效果。该方法检测结果显示:IL‑2浓度为60U/mL、IL‑21浓度为10ng/mL时,对EBV‑LMP2特异性CD8+T细胞的杀伤效率增强效果最高;单独添加终浓度为10ng/mL的IL‑21即可获得显著的免疫增强效果。结果表明,RTCA可用于实时监测IL‑2和IL‑21对T细胞功能的免疫增强效果。

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Patent Info :

Type: 发明申请

Patent No.: CN201910161068.0

Filing Date: 2019-03-04

Publication Date: 2020-09-11

Pub. No.: CN111647558A

Applicants: 北京工业大学

Legal Status: 撤回-主动撤回

Cited Count:

WoS CC Cited Count: 0

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 4

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