Here,　to　study　effects　of　lead　damper　on　seismic　performance　of　cold-formed　thin-walled　steel　whole　structure　connected　by　self-tapping　screws　and　its　feasibility,　based　on　single　wall＇s　low　cyclic　repeated　load　test　results　analysis,　the　finite　element　model　establishing　method　for　cold-formed　thin-walled　steel　wall　being　able　to　correctly　reflect　wall　hysteretic　performance　and　the　whole　structure　was　proposed.　Time-varying　damage　index　based　on　stiffness,　time-varying　damage　index　based　on　elastic-plastic　energy-dissipating　difference　and　time-varying　ductility　coefficient　were　used　to　do　deep　damage　evolution　analysis　for　cold-formed　thin-walled　steel　whole　structure　through　the　whole　structure＇s　time　history　analysis　and　damage　analysis.　A　typical　cold-formed　thin-walled　steel　office　building　structure＇s　dynamic　model　was　established　to　do　its　dynamic　time　history　analysis,　and　study　its　seismic　effect　under　earthquakes　with　different　amplitudes.　The　results　showed　that　lead　damper　can　not　only　improve　mechanical　and　seismic　performance　of　single　shear　wall,　but　also　reduce　dynamic　responses　and　damage　degrees　of　cold-formed　thin-walled　steel　whole　structure　under　large　earthquake;　this　whole　structure　with　lead　damper　has　good　seismic　performance　and　application　prospect.　©　2021,　Editorial　Office　of　Journal　of　Vibration　and　Shock.　All　right　reserved.