This　paper　introduces　the　exponential　stabilization　issue　of　coupled　delayed　ODE-PDE　systems　with　packet　losses.　By　using　a　Lyapunov-Krasovskii　functional　(LKF),　a　control　scheme　respected　packet　losses　is　developed　by　space-dependent　linear　matrix　inequalities　(SDLMIs)　to　guarantee　the　mean　square　exponential　stability　(MSES)　for　the　closed-loop　coupled　delayed　ODE-PDE　system.　Finally,　the　control　approach　is　proved　effective　by　taking　a　hypersonic　rocket　car　(HRC)　as　an　example.　©　2022　IEEE.