Cell　microinjection　has　been　widely　used　in　medical　and　biological　research　because　of　its　high　transmission　efficiency　and　low　toxicity.　The　overlarge　deformation　of　cells　during　microinjection　is　one　important　potential　reason　for　its　low　survival　rate　after　injection.　Therefore,　there　are　the　existing　studies　that　have　tried　to　established　linear　mechanic　deformation　models　of　biological　cells　under　microinjection.　In　this　paper,　based　on　electrothermally　driven　microclamps,　a　nonlinear　viscoelastic　model　is　established　to　estimate　the　deformation　of　a　Zebrafish　embryo　clamped　by　a　microgripper　during　microinjection.　Firstly,　a　nonlinear　viscoelastic　model　is　proposed　to　describe　the　dynamic　behavior　with　respect　to　injection　speed,　cell　deformation,　and　puncture　force　of　Zebrafish　embryos　during　injection.　Secondly,　microinjection　experiments　of　Zebrafish　embryos　are　conducted　to　measure　the　injection　force　and　deformation　at　different　injection　speeds.　Finally,　the　parameters　of　the　nonlinear　viscoelastic　model　are　identified　with　the　experimental　results,　and　the　proposed　model　in　this　paper　is　compared　with　the　existing　linear　model　in　terms　of　accuracy.　©　2021　ACM.