Based　on　China’s　real　estate　investment　(REI),　commercial　housing　sales　(CHS),　and　GDP　data　from　2001　to　2020,　we　studied　the　dependence,　asymmetry,　and　transmission　direction　of　China’s　real　estate　and　economy.　Their　cross-correlation　is　demonstrated　through　the　deep　crosscorrelation　analysis　(DCCA)　algorithm,　multifractal　asymmetric　detrended　cross-correlation　analysis　(MF-ADCCA)　algorithm　and　DCCA　algorithm　based　on　a　time　delay.　Both　REI　and　CHS　have　persistence　with　GDP.　The　real　estate　industry　and　economy　have　asymmetric　multifractal　characteristics.　Meanwhile,　real　estate　and　the　economy　have　different　trends,　and　they　can　affect　each　other　with　the　same　length　of　time　delay.　This　effect　diminishes　in　a　short　period　of　time,　and　there　are　unsteady　fluctuations　in　cross-correlation　persistence　in　the　long　term.　©　2021,　Science　Press　(China).　All　rights　reserved.