Under　the　combination　of　certain　corrosive　ions　and　stress,　Cu-Ni　alloys　may　experience　severe　stress　corrosion　cracking　(SCC),　which　causes　premature　failure　and　hinders　their　further　applications　as　crucial　construction　materials　in　various　engineering　fields.　To　reveal　the　origin　of　such　failure,　minimize　the　related　negative　impacts,　and　achieve　economic　and　social　benefits,　this　review　summarizes　all　SCC-related　issues　by　making　a　brief　introduction　to　Cu-Ni　alloys,　reporting　the　SCC　behavior　in　various　environments,　identifying　the　effects　of　different　factors　during　SCC,　and　revealing　the　SCC　degradation　mechanisms.　S2−　and　NH4+　are　the　prominent　SCC　initiators　since　the　former　can　combine　with　Cu+　to　form　Cu2S　as　a　non-protective　corrosion　product,　while　the　latter　has　a　great　tendency　to　react　with　Cu2O/Cu　and　accelerate　the　general　or　local　dissolution.　Their　combination　has　the　most　detrimental　effect.　The　SCC　mechanisms　of　Cu-Ni　alloys　are　summarized　as　film　rupture　theory　and　dealloying　theory.　The　related　SCC　mitigation　strategies,　including　using　inhibitors,　tailoring　alloying　elements,　and　removing/reducing　the　stress　are　also　discussed.　In　addition,　future　directions　are　made　at　the　end　of　this　paper.　©　2023　by　the　authors.