The　compatibility　between　waste　plastic　polymers　and　bitumen　is　the　most　challenging　issue　hindering　the　improvement　of　modified　bitumen　performance.　The　current　practice　of　recycled　waste　plastics　includes　the　use　of　polyvinyl　chloride　(PVC),　polypropylene　(PP),　polyethylene　(PE),　etc.　This　study　was　designed　to　investigate　the　compatibility　of　different　waste　plastic　polymers　with　bitumen　binders　by　conducting　molecular　dynamics　(MD)　simulations　at　different　temperatures.　The　molecular　models　of　these　materials　were　constructed　in　this　study　for　the　compatibility　analysis,　and　they　include　the　base　bitumen,　polymers　(PVC,　PP,　and　PE),　polymer-bitumen　blending　systems.　Using　the　output　and　related　calculations　of　these　MD　models,　the　properties　of　these　blending　systems　were　measured　at　different　temperatures　through　the　calculation　of　the　solubility　parameter　(delta)　and　interaction　energies.　The　compatibility　analysis　is　discussed　in　the　context　of　these　simulation　results.　The　simulation　results　for　the　solubility　parameters　and　interaction　energies　show　consistent　trends.　The　results　showed　that　PVC　and　PP　had　better　compatibility　with　bitumen　at　433.15　K　and　that　PE　and　bitumen　had　good　compatibility　at　393.15　K.　Moreover,　it　can　be　deduced　that　the　order　of　compatibility　of　the　three　polymers　with　bitumen　is　as　follows:　PVC　＞　PE　＞　PP.　In　addition,　these　research　results　can　be　referenced　for　the　industry　and　research　development　of　modified　bitumen.