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Author:

Chen, Shiliang (Chen, Shiliang.) | Du, Tianming (Du, Tianming.) | Zhang, Hanbing (Zhang, Hanbing.) | Qi, Jing (Qi, Jing.) | Zhang, Yanping (Zhang, Yanping.) | Mu, Yongliang (Mu, Yongliang.) | Qiao, Aike (Qiao, Aike.) (Scholars:乔爱科)

Indexed by:

EI Scopus SCIE

Abstract:

Biodegradable stents can support vessels for an extended period, maintain vascular patency, and progressively degrade once vascular remodeling is completed, thereby reducing the constraints of traditional metal stents. An ideal degradable stent must have good mechanical properties, degradation behavior, and biocompatibility. Zinc has become a new type of biodegradable metal after magnesium and iron, owing to its suitable degradation rate and good biocompatibility. However, zinc's poor strength and ductility make it unsuitable as a vascular stent material. Therefore, this paper reviewed the primary methods for improving the overall properties of zinc. By discussing the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies, we found that alloying is the most common, simple, and effective method to improve mechanical properties. Deformation processing can further improve the mechanical properties by changing the microstructures of zinc alloys. Surface modification is an important means to improve the biological activity, blood compatibility and corrosion resistance of zinc alloys. Meanwhile, structural design can not only improve the mechanical properties of the vascular stents, but also endow the stents with special properties such as negative Poisson 's ratio. Manufacturing zinc alloys with excellent degradation properties, improved mechanical properties and strong biocompatibility and exploring their mechanism of interaction with the human body remain areas for future research.

Keyword:

Vascular remodeling Ideal biodegradable vascular stents Overall properties improvements Alloying of zinc

Author Community:

  • [ 1 ] [Chen, Shiliang]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 2 ] [Du, Tianming]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 3 ] [Zhang, Hanbing]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 4 ] [Qi, Jing]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 5 ] [Zhang, Yanping]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 6 ] [Qiao, Aike]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China
  • [ 7 ] [Mu, Yongliang]Northeastern Univ, Sch Met, Shenyang, Peoples R China

Reprint Author's Address:

  • [Du, Tianming]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China;;[Qiao, Aike]Beijing Univ Technol, Fac Environm & Life, Beijing, Peoples R China;;

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Source :

BIOMATERIALS ADVANCES

Year: 2023

Volume: 156

Cited Count:

WoS CC Cited Count: 14

SCOPUS Cited Count: 14

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 11

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