The　high-content　waste　rubber　powder　(WRP)-modified　asphalt　(WRMA)　has　poor　storage　stability　and　tends　to　produce　many　volatile　organic　compounds　(VOCs).　This　study　aimed　to　research　the　influence　of　incorporating　high-content　WRP　on　the　performance　enhancement　and　VOCs　emission　of　asphalt　and　its　mixtures.　The　storage　stability,　rheological　properties　and　cracking　resistance　of　WRMA　were　tested.　Further,　the　high　and　low-temperature　properties　of　WRMA　mixtures　were　evaluated.　Additionally,　the　VOCs　emission　characteristics　of　WRMA　mixtures　were　analysed　.　The　results　indicate　that　activated　WRP　has　good　compatibility　with　asphalt.　The　high-content　of　WRP　can　significantly　enhance　the　high-temperature　rheological　properties　and　low　temperature　cracking　resistance　of　asphalt　binder,　and　the　addition　of　nanometre　calcium　carbonate　(B3)　adsorbent　can　further　enhance　the　physicochemical　properties　of　asphalt　binder.　Moreover,　compared　with　70#　asphalt　mixture,　the　dynamic　stability　of　WRMA　mixture　increases　by　about　50%,　and　the　immersion　residual　stability　and　freeze-thaw　splitting　strength　values　increase　by　6.34%　and　5.98%,　respectively.　In　addition,　the　B3　adsorbent　can　significantly　reduce　the　VOCs　emission　from　WRMA　mixtures.　The　corresponding　conclusions　could　provide　guidance　for　the　large-scale　application　of　high-content　WRMA　mixtures　and　promote　cleaner　and　greener　products.