Excessive　CO2　and　food　shortage　are　two　grand　challenges　of　human　society.　Directly　converting　CO2　into　food　materials　can　simultaneously　alleviate　both,　like　what　green　crops　do　in　nature.　Nevertheless,　natural　photosynthesis　has　a　limited　energy　efficiency　due　to　low　activity　and　specificity　of　key　enzyme　D-ribulose-1,5-bisphosphate　carboxylase/oxygenase　(RuBisCO).　To　enhance　the　efficiency,　many　prior　studies　focused　on　engineering　the　enzymes,　but　this　study　chooses　to　learn　from　the　nature　to　design　more　efficient　reactors.　This　work　is　original　in　mimicking　the　stacked　structure　of　thylakoids　in　chloroplasts　to　immobilize　RuBisCO　in　a　microreactor　using　the　layer-by-layer　strategy,　obtaining　the　continuous　conversion　of　CO2　into　glucose　precursor　at　1.9　nmol　min(-1)　with　enhanced　activity　(1.5　times),　stability　(approximate　to　8　times),　and　reusability　(96%　after　10　reuses)　relative　to　the　free　RuBisCO.　The　microreactors　are　further　scaled　out　from　one　to　six　in　parallel　and　achieve　the　production　at　15.8　nmol　min(-1)　with　an　energy　conversion　efficiency　of　3.3　times　of　rice,　showing　better　performance　of　this　artificial　synthesis　than　NPS　in　terms　of　energy　conversion　efficiency.　The　exploration　of　the　potential　of　mass　production　would　benefit　both　food　supply　and　carbon　neutralization.