High-chloride　leachate　is　a　solution　rich　in　precious　metals　that　is　produced　in　chloride　hydrometallurgy.　It　has　high　levels　of　both　rare　and　precious　metals　and　hazardous　chloride　ions,　and　resource　recovery　from　this　solution　and　its　safe　disposal　have　become　key　objectives　in　the　field　of　hydrometallurgy.　In　this　study,　a　sus-tainable　process　involving　＂ultrasound-assisted　precipitation-Pb　powder　cementation＂　was　proposed　for　the　stepwise　separation　and　high-value　utilization　of　Bi,　Au　and　Ag　obtained　from　high-chloride　leachate.　Targeted　separation　and　conversion　of　Bi　were　achieved　by　precipitation-re-acid　hydrolysis-ultrasonication-assisted　coprecipitation-centrifugal　purification.　Under　the　optimal　process　conditions,　the　removal　rate　of　Bi　reached　99.52%,　while　the　loss　rates　of　Au　and　Ag　were　only　4.63%　and　8.72%,　respectively.　Single-factor　experiments　of　Au　and　Ag　cementation　by　Pb　powder　showed　that　the　recovery　rates　of　precious　metals　could　be　improved　by　increasing　the　temperature,　raising　the　solution　pH,　and　applying　mechanical　force　and　ultrasonication.　A　possible　reaction　mechanism　for　Au　and　Ag　cementation　with　Pb　powder　was　proposed　based　on　macroscopic　kinetic　analysis　and　microscopic　mineral　characterization.　This　work　provides　technical　support　and　a　theoretical　basis　for　the　separation　and　enrichment　of　rare　and　precious　metals　in　chloride　hydrometallurgy.