The　seismic　performance　of　liquefied　natural　gas　(LNG)　tanks　is　significantly　influenced　by　Soil-FoundationStructure　Interaction　(SFSI).　It　is　essential　to　investigate　the　effect　of　the　SFSI　on　isolated　LNG　tank,　particularly　on　a　deep　soil　site.　This　study　aims　to　examine　the　impact　of　the　SFSI　on　the　seismic　performance　of　an　isolated　LNG　tank　located　on　the　deep　soil　site.　The　impact　of　foundation　type,　pile　length,　and　the　frequency　content　on　the　primary　seismic　responses　of　the　LNG　tank　were　thoroughly　examined　in　this　study.　These　seismic　responses　include　the　acceleration　of　the　outer　tank,　the　height　of　the　sloshing　wave,　and　the　shear　force　and　bending　moment　of　the　inner　tank.　Additionally,　the　seismic　force　along　the　pile　foundation,　such　as　shear　force,　lateral　displacement,　and　bending　moment,　was　also　analyzed.　The　results　indicate　that　for　isolated　LNG　tanks,　it　would　be　dangerous　without　considering　the　SFSI,　while　for　the　pile　foundation,　it　may　be　beneficial　when　considering　the　SFSI.　The　pile　foundation　types　did　not　considerably　affect　the　seismic　response　of　the　isolated　LNG　tank　in　the　deep　soil　site.　Additionally,　the　seismic　response　appears　to　be　highly　sensitive　to　the　frequency　characteristics　of　the　seismic　excitation,　especially　the　low-frequency　content.