This　paper　proposes　a　One-Wire　(OWI)　digital　communication　interface　with　asynchronous　First　in　First　out　(FIFO)　buffering　function　based　on　Advanced　High-performance　Bus　(AHB-Lite),　which　adopts　half-duplex　mode　to　realize　networking　communication　between　host　and　multiple　slaves.　Based　on　this　design,　the　interface　can　be　specifically　configured　by　the　AHB-Lite　bus　for　data,　with　reading　interface　status　information,　and　supports　parity　and　glitch　filtering　filter　functions.　In　order　to　realize　the　stability　of　single-wire　communication　with　external　OWI　devices　in　the　data　transceiver　module,　the　asynchronous　FIFO　buffer　function　is　added.　During　the　data　transmission　process,　FIFO　can　buffer　single-threaded　data.　The　finite　state　machine　method　is　used　to　control　the　transmission　timing　of　the　OWI　interface,　and　Register　Transfer　Level　(RTL)　simulation　is　carried　out,　which　shows　that　the　design　can　reduce　the　use　of　hardware　resources　and　has　good　practicability.　©　2023　IEEE.